GLYCINE, AN AMINO ACID THAT IMROVES SLEEP

New Therapeutic Strategy for Amino Acid Medicine: Glycine Improves the Quality of Sleep Makoto Bannai1,* and Nobuhiro Kawai1 1Frontier Research Laboratories, Institute for Innovation, Ajinomoto Co., Inc., Kawasaki, Kanagawa 210-8681, Japan Journl of Pharmacological Sciences July 24,...

PHOSPHATIDYLSERINE IN THE BRAIN: METABOLISM AND FUNCTION

Phosphatidylserine in the Brain: Metabolism and Function Hee-Yong Kim, Bill X. Huang, and Arthur A. Spector Laboratory of Molecular Signaling, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892-9410 United States Prog...

ENDOTOXIN HYPOTHESIS OF NEURODEGENERATION

The endotoxin hypothesis of neurodegeneration Guy C Brown 1,✉ J Neuroinflammation . 2019 Sep 13;16:180. doi: 10.1186/s12974-019-1564-7 Abstract The endotoxin hypothesis of neurodegeneration is the hypothesis that endotoxin causes or contributes to neurodegeneration. Endotoxin is a lipopolysaccharide (LPS),...

“BRAIN ON FIRE” NEUROINFLAMMATION IN PSYCHIATRIC DISORDERS

The Role of Neuroinflammation in Psychiatric Disorders Michael Levin* Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Maryland, USA Perspective - Neuroscience and Psychiatry: Open Access (2024) Volume 7, Issue 5 https://www.openaccessjournals.com/articles/the-role-of-neuroinflammation-in-psychiatric-disorders-18224.html Introduction Neuroinflammation refers to the inflammatory...

50% OF TREATMENT EFFECT IS DUE TO BELIEF IN THE TREATMENT (PLACEBO EFFECT)

Placebo response and effect in randomized clinical trials: meta-research with focus on contextual effects Sigurlaug H Hafliðadóttir 1,2, Carsten B Juhl 2,3, Sabrina M Nielsen 1,4, Marius Henriksen 5, Ian A Harris 6,7,8, Henning Bliddal 5, Robin Christensen 1,4,✉ Trials. 2021 Jul 26;22:493. doi: 10.1186/s13063-021-05454-8 PMCID: PMC8314506  PMID: 34311793 Abstract Background Contextual...

MITOCHONDRIA, ESTROGEN AND THE AGING FEMALE BRAIN

MITOCHONDRIA, ESTROGEN AND FEMALE BRAIN AGING Imane Lejri 1,2,  Amandine Grimm 1,2  Neurobiology Lab for Brain Aging and Mental Health, Trans faculty Research Platform Molecular and Cognitive Neuroscience, University of Basel, Basel, Switzerland  Psychiatric University Clinics, University of Basel, Basel,...

DOPAMINE – FROM REWARD TO DISEASE

FROM REWARD TO ANHEDONIA-DOPAMINE FUNCTION IN THE GLOBAL MENTAL HEALTH CONTEXT Birgitta Dresp-Langley 1  Biomedicines . 2023 Sep 6;11(9):2469. doi https://pmc.ncbi.nlm.nih.gov/articles/PMC10525914/ Abstract When “hijacked” by compulsive behaviors that affect the reward and stress centers of the brain, functional changes...